Short-term effects of selenium supplementation of cows' feed on the content and distribution of selenium, copper and zinc in bovine milk, whey and blood plasma.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
AbstractThe effect of selenium supplementation of feed on the Se content in bovine milk, whey and plasma, and on the distribution of Se, Zn and Cu in whey and plasma was investigated. In a cross-over study two groups of cows were given a basal feed with 0.16 ppm selenite (approx. 3 mg Se/d) with or without 25 mg yeast Se/d for 2 weeks. In the supplemented group the Se content increased 10-fold in milk, 10-fold in whey and 2-fold in plasma, and after the cessation of the supplementation, selenium in milk decreased with a calculated half-life of 3.5 d. In another experiment, two groups of cows were given either 100 mg yeast Se/d for 1 week or only the basal feed. The increase in Se content in both whole and defatted milk was 40-50-fold, and in whey it was approx. 20-fold. Size-exclusion chromatography of whey using inductively coupled plasma mass spectrometry for detection showed that supplementation increased the proportion of Se in the beta-lactoglobulin-alpha-lactalbumin fraction. Distribution of Cu and Zn was essentially unaffected. In plasma, supplementation increased the Se content in all major Se fractions like selenoprotein P, albumin and low-molecular-weight compounds, but the distribution profiles of Zn and Cu underwent no major changes. The study showed for the first time the rapid kinetics of the Se increase and decrease in milk after the initiation and cessation of supplementation, respectively, and the preferential appearance of Se in the beta-lactoglobulin-alpha-lactalbumin fraction of whey. Milk highly enriched in selenium will be a useful tool for different research purposes.
CitationJ. Dairy Res. 2008, 75 (3):326-334
JournalThe Journal of dairy research
- Effect of selenate as a feed supplement to dairy cows in comparison to selenite and selenium yeast.
- Authors: Ortman K, Pehrson B
- Issue date: 1999 Dec
- Separation of selenium, zinc, and copper compounds in bovine whey using size exclusion chromatography linked to inductively coupled plasma mass spectrometry.
- Authors: Hoac T, Lundh T, Purup S, Onning G, Sejrsen K, Akesson B
- Issue date: 2007 May 16
- Selenium content and distribution in cow's milk supplemented with two dietary selenium sources.
- Authors: Muñiz-Naveiro O, Domínguez-González R, Bermejo-Barrera A, Cocho de Juan JA, Fraga Bermúdez JM, Goris Pereiras A, López Santamariña A, Martínez Lede I, Valledor Puente J, Fernández-Couto Gómez L, Bermejo-Barrera P
- Issue date: 2005 Dec 14
- Comparisons of selenite and selenium yeast feed supplements on Se-incorporation, mastitis and leucocyte function in Se-deficient dairy cows.
- Authors: Malbe M, Klaassen M, Fang W, Myllys V, Vikerpuur M, Nyholm K, Sankari S, Suoranta K, Sandholm M
- Issue date: 1995 Apr
- Effect of duration and level of supplementation of diets of lactating dairy cows with selenized yeast on selenium concentrations in milk and blood after the withdrawal of supplementation.
- Authors: Stockdale CR, Gill HS
- Issue date: 2011 May