Cytological value of sputum in workers daily exposed to air pollution.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
AbstractIn this study, quantitative modifications of dust cells, siderocytes, Curschmann's spirals and asbestos bodies and qualitative modifications (cellular changes and inflammatory infiltrate) in the sputum of 164 traffic police officers and 218 railway workers, occupationally exposed to environmental pollution, and the sputum of 119 inhabitants of a rural area, were evaluated. The results were correlated with time of exposure and smoking habits. Seventy-three (45%) traffic police officers (TPO), 76 (35%) railway workers (RW) and 29 (24%) of the rural population (RP) were smokers. The sputum, collected over a 3-day period, was smeared on glass slides and stained according to the Papanicolaou, Perl and yellow eosin methods. The results of the qualitative cytological diagnosis revealed a statistically significant difference between the TPO, RW and the RP (p < 0.001). The results of the qualitative and quantitative cytological examinations were not significantly correlated to time of occupational exposure, which was considered to be a continuous variable. The qualitative cytological examination of sputa was not statistically significant for the smoking habits of the TPO and the RP, but was significant for the RW (p < 0.0067). In the TPO, the number of dust cells was higher in smokers, and the relative risk (RR) was 3.95. In the RW, the RR was 2.84. The results of our study revealed that for the RW, the qualitative-quantitative cytological alterations in sputum were due much more to smoking habits than to occupational exposure, while the presence of asbestos bodies correlated with work activity. The qualitative-quantitative cytological examinations of the TPO differed significantly from that of the other two populations.
CitationAnticancer Res. 2006, 26 (1A):395-403
DescriptionKEYWORDS - CLASSIFICATION:analysis;Adult;Aged;Aged,80 and over;Air Pollutants;Asbestos;biomarkers of exposure & effect: field studies;chemistry;cytology;diagnosis;Dust;Female;Humans;Inhalation Exposure;Italy;methods;Male;Middle Aged;Occupational Exposure;Police;Railroads;Research;Rural Population;Smoking;Sputum.
- Carbon and hemosiderin-laden macrophages in sputum of traffic policeman exposed to air pollution.
- Authors: Giovagnoli MR, Alderisio M, Cenci M, Nofroni I, Vecchione A
- Issue date: 1999 Jul-Aug
- Asbestos bodies in the sputum of workers exposed to environmental pollution.
- Authors: Alderisio M, Giovagnoli MR, Cenci M, Vecchione A
- Issue date: 1996 Sep-Oct
- [The effect of sex factors on cytologic changes in the sputum of young adults exposed to urban air pollution].
- Authors: Djuricić S, Plamenac P
- Issue date: 1999 Jan-Feb
- Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer.
- Authors: Kettunen E, Salmenkivi K, Vuopala K, Toljamo T, Kuosma E, Norppa H, Knuutila S, Kaleva S, Huuskonen MS, Anttila S
- Issue date: 2006 Nov
- Sputum induced cellularity in a group of traffic policemen.
- Authors: Dragonieri S, Musti M, Izzo C, Esposito LM, Foschino Barbaro MP, Resta O, Spanevello A
- Issue date: 2006 Aug 15