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dc.contributor.authorSantonen, Tiina
dc.contributor.authorAlimonti, Alessandro
dc.contributor.authorBocca, Beatrice
dc.contributor.authorDuca, Radu Corneliu
dc.contributor.authorGalea, Karen S
dc.contributor.authorGodderis, Lode
dc.contributor.authorGöen, Thomas
dc.contributor.authorGomes, Bruno
dc.contributor.authorHanser, Ogier
dc.contributor.authorIavicoli, Ivo
dc.contributor.authorJanasik, Beata
dc.contributor.authorJones, Kate
dc.contributor.authorKiilunen, Mirja
dc.contributor.authorKoch, Holger M
dc.contributor.authorLeese, Elizabeth
dc.contributor.authorLeso, Veruscka
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorNdaw, Sophie
dc.contributor.authorPorras, Simo P
dc.contributor.authorRobert, Alain
dc.contributor.authorRuggieri, Flavia
dc.contributor.authorScheepers, Paul T J
dc.contributor.authorSilva, Maria J
dc.contributor.authorViegas, Susana
dc.contributor.authorWasowicz, Wojciech
dc.contributor.authorCastano, Argelia
dc.contributor.authorSepai, Ovnair
dc.date.accessioned2020-01-15T09:28:43Z
dc.date.available2020-01-15T09:28:43Z
dc.date.issued2019-10-01
dc.identifier.citationEnvironmental Research 2019; 177: art.108583.en_US
dc.identifier.issn1096-0953
dc.identifier.pmid31330491
dc.identifier.doi10.1016/j.envres.2019.108583
dc.identifier.urihttp://hdl.handle.net/10146/618339
dc.description.abstractThe EU human biomonitoring initiative, HBM4EU, aims to co-ordinate and advance human biomonitoring (HBM) across Europe. Within its remit, the project is gathering new, policy relevant, EU-wide data on occupational exposure to relevant priority chemicals and developing new approaches for occupational biomonitoring. In this manuscript, the hexavalent chromium [Cr(VI)] study design is presented as the first example of this HBM4EU approach. This study involves eight European countries and plans to recruit 400 workers performing Cr(VI) surface treatment e.g. electroplating or stainless steel welding activities. The aim is to collect new data on current occupational exposure to Cr(VI) in Europe and to test new methods for Cr biomonitoring, specifically the analysis of Cr(VI) in exhaled breath condensate (EBC) and Cr in red blood cells (RBC) in addition to traditional urinary total Cr analyses. Furthermore, exposure data will be complemented with early biological effects data, including genetic and epigenetic effects. Personal air samples and wipe samples are collected in parallel to help informing the biomonitoring results. We present standard operational procedures (SOPs) to support the harmonized methodologies for the collection of occupational hygiene and HBM samples in different countries.en_US
dc.language.isoenen_US
dc.relation.urlhttps://www.sciencedirect.com/science/article/pii/S0013935119303809en_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectBiomonitoringen_US
dc.subjectEffect markersen_US
dc.subjectElectroplatingen_US
dc.subjectExhaled breath condensateen_US
dc.subjectHexavalent chromiumen_US
dc.subjectMulticenter studyen_US
dc.subjectOccupational exposureen_US
dc.subjectWeldingen_US
dc.titleSetting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium.en_US
dc.typeArticleen_US
dc.contributor.departmentNofer Institute of Occupational Medicineen_US
dc.identifier.journalEnvironmental Researchen_US
dc.source.journaltitleEnvironmental research
refterms.dateFOA2020-01-15T09:28:43Z


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