Show simple item record

dc.contributor.authorDziewirska, Emila
dc.contributor.authorRadwan, Michał
dc.contributor.authorWielgomas, Bartosz
dc.contributor.authorKlimowska, Anna
dc.contributor.authorRadwan, Paweł
dc.contributor.authorKałużny, Paweł
dc.contributor.authorHanke, Wojciech
dc.contributor.authorSłodki, Maciej
dc.contributor.authorJurewicz, Joanna
dc.date.accessioned2020-01-14T12:15:49Z
dc.date.available2020-01-14T12:15:49Z
dc.date.issued2019
dc.identifier.citationAmerican Journal of Men's Health, Volume: 13 issue: 1en_US
dc.identifier.issn1557-9891
dc.identifier.pmid30813854
dc.identifier.doi10.1177/1557988318816598
dc.identifier.urihttp://hdl.handle.net/10146/618334
dc.description.abstractThe aim of the study was to evaluate the association between environmental exposure to nonpersistent insecticides and semen quality (concentration, motility, morphology, computer-aided semen analysis [CASA] parameters, and sperm DNA damage). Urine samples (n = 315) collected from men who attended the infertility clinic with normal semen concentration of 15 to 300 mln/ml and age under 45 years were analyzed for two metabolites (1-naphthol [1N] and 3,5,6-trichloro-2-pyridinol [TCPY]) of nonpersistent insecticides. Participants provided semen, blood, and saliva samples; additionally, men filled a detailed questionnaire. The results identified that urinary TCPY concentration was significantly associated with a decrease in motility; also there was a positive association between TCPY and DNA fragmentation index (DFI). 1N concentration was negatively associated with a percentage of sperm with normal morphology and positively with one of the CASA parameters (curvilinear velocity [VCL]). The results suggest that environmental exposure to nonpersistent insecticides may have an impact on semen quality parameters and sperm DNA damage.en_US
dc.language.isoenen_US
dc.relation.urlhttps://journals.sagepub.com/doi/full/10.1177/1557988318816598en_US
dc.rightsAttribution-NonCommercial 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/us/*
dc.subjectDNA damageen_US
dc.subjectcarbarylen_US
dc.subjectchlorpyrifosen_US
dc.subjectsemen qualityen_US
dc.titleHuman Semen Quality, Sperm DNA Damage, and the Level of Urinary Concentrations of 1N and TCPY, the Biomarkers of Nonpersistent Insecticides.en_US
dc.typeArticleen_US
dc.contributor.departmentNofer Institute of Occupational Medicineen_US
dc.identifier.journalAmerican Journal of Men's Healthen_US
dc.source.journaltitleAmerican journal of men's health
refterms.dateFOA2020-01-14T12:15:50Z


Files in this item

Thumbnail
Name:
humen semen.pdf
Size:
104.9Kb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial 3.0 United States