Human Semen Quality, Sperm DNA Damage, and the Level of Urinary Concentrations of 1N and TCPY, the Biomarkers of Nonpersistent Insecticides.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
AffiliationNofer Institute of Occupational Medicine
MetadataShow full item record
AbstractThe aim of the study was to evaluate the association between environmental exposure to nonpersistent insecticides and semen quality (concentration, motility, morphology, computer-aided semen analysis [CASA] parameters, and sperm DNA damage). Urine samples (n = 315) collected from men who attended the infertility clinic with normal semen concentration of 15 to 300 mln/ml and age under 45 years were analyzed for two metabolites (1-naphthol [1N] and 3,5,6-trichloro-2-pyridinol [TCPY]) of nonpersistent insecticides. Participants provided semen, blood, and saliva samples; additionally, men filled a detailed questionnaire. The results identified that urinary TCPY concentration was significantly associated with a decrease in motility; also there was a positive association between TCPY and DNA fragmentation index (DFI). 1N concentration was negatively associated with a percentage of sperm with normal morphology and positively with one of the CASA parameters (curvilinear velocity [VCL]). The results suggest that environmental exposure to nonpersistent insecticides may have an impact on semen quality parameters and sperm DNA damage.
CitationAmerican Journal of Men's Health, Volume: 13 issue: 1
JournalAmerican Journal of Men's Health
The following license files are associated with this item:
Except where otherwise noted, this item's license is described as Attribution-NonCommercial 3.0 United States
- The relationship of urinary metabolites of carbaryl/naphthalene and chlorpyrifos with human semen quality.
- Authors: Meeker JD, Ryan L, Barr DB, Herrick RF, Bennett DH, Bravo R, Hauser R
- Issue date: 2004 Dec
- Exposure to nonpersistent insecticides and male reproductive hormones.
- Authors: Meeker JD, Ryan L, Barr DB, Hauser R
- Issue date: 2006 Jan
- Urinary levels of insecticide metabolites and DNA damage in human sperm.
- Authors: Meeker JD, Singh NP, Ryan L, Duty SM, Barr DB, Herrick RF, Bennett DH, Hauser R
- Issue date: 2004 Nov
- Temporal variability of urinary levels of nonpersistent insecticides in adult men.
- Authors: Meeker JD, Barr DB, Ryan L, Herrick RF, Bennett DH, Bravo R, Hauser R
- Issue date: 2005 May
- Thyroid hormones in relation to urinary metabolites of non-persistent insecticides in men of reproductive age.
- Authors: Meeker JD, Barr DB, Hauser R
- Issue date: 2006 Oct