[Application of recombinant latex allergens in diagnostics of occupational latex allergy].
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Issue Date
2015
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Show full item recordAbstract
Over many years, allergy to natural rubber latex has been a major problem among health care workers (HCW). The diagnosis of occupational allergy requires methods of high diagnostic accuracy in view of certification implications (e.g., a sick worker quits a job). With the development of molecular methods, the frequency of application of recombinant allergens it the diagnostics of allergic diseases continues to increase. This paper reviews the applicability of laboratory tests which use recombinant allergens in the diagnostics of occupational allergy. The diagnosis of latex allergy is based on the presence of clinical symptoms linked with exposure to latex allergens, positive skin prick tests and detection of specific IgE antibodies to latex in serun. Moreover, in some cases specific challenge tests are conducted. The analysis of literature indicates that applying the panel of recombinant latex allergens in diagnostic tests, cross-reactivity can very likely be excluded and/or sensitization can be confirmed without the need for specific challenge tests, which in case of latex allergens carries a potential risk of aeneralized reactions.Citation
Med Pr 2015, 66 (1):85-97Journal
Medycyna PracyPubMed ID
26016048Additional Links
http://medpr.imp.lodz.pl/Zastosowanie-alergenow-rekombinowanych-w-diagnostyce-zawodowej-alergii-na-lateks,1952,0,2.htmlType
ArticleLanguage
plISSN
0465-5893Sponsors
IMP 11.3 pt. „Zastosowanie alergenowo swoistych przeciwciał IgE dla alergenów rekombinowanych w diagnostyce alergii zawodowej na lateks”.Collections
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