• Prenatal and postnatal exposure to air pollution and emotional and aggressive symptoms in children from 8 European birth cohorts.

      Jorcano, Ainhoa; Lubczyńska, Małgorzata J; Pierotti, Livia; Altug, Hicran; Ballester, Ferran; Cesaroni, Giulia; El Marroun, Hanan; Fernández-Somoano, Ana; Freire, Carmen; Hanke, Wojciech; et al. (2019-01-01)
      We analysed data of 13182 children from 8 European population-based birth cohorts. Concentrations of nitrogen dioxide (NO2), nitrogen oxides (NOx), particulate matter (PM) with diameters of ≤10 μm (PM10), ≤ 2.5 μm (PM2.5), and between 10 and 2.5 μm (PMcoarse), the absorbance of PM2.5 filters (PM2.5abs), and polycyclic aromatic hydrocarbons (PAHs) were estimated at residential addresses of each participant. Depressive and anxiety symptoms and aggressive symptoms were assessed at 7-11 years of age using parent reported tests. Children were classified in borderline/clinical range or clinical range using validated cut offs. Region specific models were adjusted for various socio-economic and lifestyle characteristics and then combined using random effect meta-analysis. Multiple imputation and inverse probability weighting methods were applied to correct for potential attrition bias.