International studies of prenatal exposure to polycyclic aromatic hydrocarbons and fetal growth.
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Authors
Choi, HyunokJedrychowski, Wieslaw
Spengler, John
Camann, David E.
Whyatt, Robin M.
Rauh, Virginia
Tsai, Wei-Yann
Perera, Frederica P.
Issue Date
2006-11
Metadata
Show full item recordAbstract
OBJECTIVES: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitously distributed human mutagens and carcinogens. However, lack of adequate air monitoring data has limited understanding of the effects of airborne PAHs on fetal growth. To address this gap in knowledge, we examined the association between prenatal exposure to airborne PAHs and birth weight, birth length, and birth head circumference, respectively, in Krakow, Poland, and New York City (NYC). METHODS: The parallel prospective cohort studies enrolled nonsmoking, healthy, and nonoccupationally exposed women and their newborns. Personal air monitoring of pregnant women was conducted over 48 hr. To control for maternal environmental tobacco smoke (ETS) exposure, we excluded those with umbilical cord plasma cotinine concentrations > 25 ng/mL. Mean cord plasma cotinine concentrations in both ethnic groups wereCitation
Environ. Health Perspect. 2006, 114 (11):1744-1750PubMed ID
17107862Additional Links
http://www.ehponline.org/members/2006/8982/8982.htmlhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17107862
Type
ArticleLanguage
enDescription
Biomarkers of exposure & effect: validation & field studiesISSN
0091-6765Collections
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