Antiproliferative activity of extracts of some Bolivian medicinal plants.
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Issue Date
2010-11-04
Metadata
Show full item recordAbstract
Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity of the extracts was correlated with the phytochemical characterization. Further studies of the mechanism of action of the bioactive extracts are needed.Citation
J. Med. Plant. Res. 2010, 4:2204-2210Additional Links
http://www.academicjournals.org/JMPR/abstracts/abstracts/abstracts2010/4Nov/Rodrigo%20et%20al.htmType
ArticleLanguage
enISSN
1996-0875Sponsors
This research was supported by Swedish International Development Agency (Sida) by funding a joint project on Plant Biodiversity between Major University of San Andres, La Paz, Bolivia and Lund University, Sweden. Some support was obtained from the EU NoE ECNIS (513943).Collections