Nanorurki weglowe - charakterystyka substancji, dzialanie biologiczne i dopuszczalne poziomy narazenia zawodowego.

2.50
Hdl Handle:
http://hdl.handle.net/10146/618132
Title:
Nanorurki weglowe - charakterystyka substancji, dzialanie biologiczne i dopuszczalne poziomy narazenia zawodowego.
Authors:
Swidwińska-Gajewska, Anna Maria; Czerczak, Slawomir
Other Titles:
Carbon nanotubes - Characteristic of the substance, biological effects and occupational exposure levels.
Abstract:
Carbon nanotubes (CNTs) are a diverse group of nano-objects in terms of structure, size (length, diameter), shape and characteristics. The growing interest in these structures is due to the increasing number of people working in exposure to CNTs. Occupational exposure to carbon nanotubes may occur in research laboratories, as well as in plants producing CNTs and their nanocomposites. Carbon nanotubes concentration at the emission source may reach 107 particles/cm<sup>3</sup>. These values, however, are considerably reduced after the application of adequate ventilation. Animal studies suggest that the main route of exposure is inhalation. Carbon nanotubes administered orally are largely excreted in the feces. In animals exposed by inhalation, CNTs caused mainly inflammation, as a result of oxidative stress, leading above all to changes in the lungs. The main effect of animal dermal exposure is oxidative stress causing local inflammation. In animals exposed by ingestion the mild or no toxicity was observed. Carbon nanotubes did not induce mutations in the bacterial tests, but they were genotoxic in a series of tests on cells in vitro, as well as in exposed mice in vivo. Embryotoxicity of nanotubes depends mainly on their modifications and carcinogenicity - primarily on the CNT size and its rigidity. Occupational exposure limits for CNTs proposed by world experts fall within the range of 1-80 μg/m<sup>3</sup>. The different effects of various kinds of CNT, leads to the conclusion that each type of nanotube should be treated as a separate substance with individual estimation of hygienic normative. Med Pr 2017;68(2):259-276.
Affiliation:
Nofer Institute of Occupational Medicine, Lodz, Poland
Citation:
Medycyna Pracy 2017 Mar 24;68(2):259-276.
Journal:
Medycyna Pracy
Issue Date:
24-Mar-2017
URI:
http://hdl.handle.net/10146/618132
DOI:
10.13075/mp.5893.00504
PubMed ID:
28345685
Additional Links:
http://medpr.imp.lodz.pl/Nanorurki-weglowe-charakterystyka-substancji-dzialanie-biologiczne-oraz-dopuszczalne-poziomy-narazenia-zawodowego,64214,0,2.html
Type:
Article
Language:
pl
ISSN:
0465-5893
Sponsors:
Finansowanie / Funding: w ramach dotacji na działalność statutową, zadanie nr IMP 24.10/2013 pt. „Analiza ryzyka związanego z nanotechnologiami pod kątem wyznaczenia dopuszczalnych poziomów w środowisku pracy dla 4 substancji w postaci nanocząstek”. Kierownik tematu: mgr Anna Maria Świdwińska-Gajewska.
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorSwidwińska-Gajewska, Anna Mariaen
dc.contributor.authorCzerczak, Slawomiren
dc.date.accessioned2017-08-22T12:06:25Z-
dc.date.available2017-08-22T12:06:25Z-
dc.date.issued2017-03-24-
dc.identifier.citationMedycyna Pracy 2017 Mar 24;68(2):259-276.en
dc.identifier.issn0465-5893-
dc.identifier.pmid28345685-
dc.identifier.doi10.13075/mp.5893.00504-
dc.identifier.urihttp://hdl.handle.net/10146/618132-
dc.description.abstractCarbon nanotubes (CNTs) are a diverse group of nano-objects in terms of structure, size (length, diameter), shape and characteristics. The growing interest in these structures is due to the increasing number of people working in exposure to CNTs. Occupational exposure to carbon nanotubes may occur in research laboratories, as well as in plants producing CNTs and their nanocomposites. Carbon nanotubes concentration at the emission source may reach 107 particles/cm<sup>3</sup>. These values, however, are considerably reduced after the application of adequate ventilation. Animal studies suggest that the main route of exposure is inhalation. Carbon nanotubes administered orally are largely excreted in the feces. In animals exposed by inhalation, CNTs caused mainly inflammation, as a result of oxidative stress, leading above all to changes in the lungs. The main effect of animal dermal exposure is oxidative stress causing local inflammation. In animals exposed by ingestion the mild or no toxicity was observed. Carbon nanotubes did not induce mutations in the bacterial tests, but they were genotoxic in a series of tests on cells in vitro, as well as in exposed mice in vivo. Embryotoxicity of nanotubes depends mainly on their modifications and carcinogenicity - primarily on the CNT size and its rigidity. Occupational exposure limits for CNTs proposed by world experts fall within the range of 1-80 μg/m<sup>3</sup>. The different effects of various kinds of CNT, leads to the conclusion that each type of nanotube should be treated as a separate substance with individual estimation of hygienic normative. Med Pr 2017;68(2):259-276.en
dc.description.sponsorshipFinansowanie / Funding: w ramach dotacji na działalność statutową, zadanie nr IMP 24.10/2013 pt. „Analiza ryzyka związanego z nanotechnologiami pod kątem wyznaczenia dopuszczalnych poziomów w środowisku pracy dla 4 substancji w postaci nanocząstek”. Kierownik tematu: mgr Anna Maria Świdwińska-Gajewska.en
dc.languagepol-
dc.language.isoplen
dc.relation.urlhttp://medpr.imp.lodz.pl/Nanorurki-weglowe-charakterystyka-substancji-dzialanie-biologiczne-oraz-dopuszczalne-poziomy-narazenia-zawodowego,64214,0,2.htmlen
dc.rightsArchived with thanks to Medycyna pracyen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectcarbon nanotubesen
dc.subjectinhalationen
dc.subjectnanofibersen
dc.subjectnanoobjectsen
dc.subjectoccupational expoureen
dc.subjecttoxicityen
dc.titleNanorurki weglowe - charakterystyka substancji, dzialanie biologiczne i dopuszczalne poziomy narazenia zawodowego.pl
dc.title.alternativeCarbon nanotubes - Characteristic of the substance, biological effects and occupational exposure levels.en
dc.typeArticleen
dc.contributor.departmentNofer Institute of Occupational Medicine, Lodz, Polanden
dc.identifier.journalMedycyna Pracyen

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