Analiza zmian w obrazie radiologicznym pluc i zaburzen czynnosci wentylacyjnej pluc u pracownikow zawodowo narazonych na azbest chryzotylowy w przeszlosci.

2.50
Hdl Handle:
http://hdl.handle.net/10146/618128
Title:
Analiza zmian w obrazie radiologicznym pluc i zaburzen czynnosci wentylacyjnej pluc u pracownikow zawodowo narazonych na azbest chryzotylowy w przeszlosci.
Authors:
Cwynar, Elzbieta; Swiątkowska, Beata; Tomczyk, Jarosław
Other Titles:
Analysis of changes in radiographic lung image and lung ventilation disorders in workers occupationally exposed to chrysotile in the past.
Abstract:
The adverse health effects of occupational exposure to asbestos dust may occur several years after first exposure. The objective of the study was to assess the relationship between lesions in the respiratory system and the factors contributing to occupational exposure to asbestos described in the first medical examination as well as to analyze the factors responsible for the progression of these changes in further medical tests.; The study group comprised 591 former workers of asbestos processing plant "Gambit" in Lubawka. The results of medical examinations carried out in 2001-2012 were assessed. Statistical inference was performed based on bilateral significance tests at the 0.05 level of significance.; A higher risk of interstitial lung changes along with an increase in the cumulative concentration of asbestos was indicated; for the employees with the highest exposure, the adjusted odds ratio (OR) was 1.63 (95% confidence interval (CI): 0.99-2.71), while for changes with the severity degree qualifying for asbestosis diagnosis, the risk was significantly increased, over fivefold higher, compared to subjects employed in the lowest exposure. The analysis of the relationship between the progression of interstitial changes and the exposure to asbestos dust showed a fourfold higher risk of the progression in workers employed in the highest exposure. Mean values of FEV1 (forced expiratory volume in 1 s), FVC (forced vital capacity), FEV1/FVC (forced expiratory volume in 1 s to forced vital capacity) were significantly lower in the subjects working in a higher asbestos exposure. The effect of tobacco smoking on the occurrence of interstitial lung changes and their progression was also confirmed.; The results of prophylactic medical examinations of the health status of workers formerly employed in the plants using chrysotile indicate the importance andthe need for a long-term clinical follow-up and the promotion of anti-smoking prevention in this group of former employees. Med Pr 2017;68(2):247-258.
Affiliation:
Nofer Institute of Occupational Medicine, Lodz, Poland
Citation:
Medycyna Pracy 2017 Mar 24;68(2):247-258.
Journal:
Medycyna Pracy
Issue Date:
24-Mar-2017
URI:
http://hdl.handle.net/10146/618128
DOI:
10.13075/mp.5893.00501
PubMed ID:
28345684
Additional Links:
http://medpr.imp.lodz.pl/Analiza-zmian-w-obrazie-radiologicznym-pluc-i-zaburzen-czynnosci-wentylacyjnej-pluc-u-pracownikow-zawodowo-narazonych-na-azbest-chryzotylowy-w-przeszlosci,64468,0,2.html
Type:
Article
Language:
pl
ISSN:
0465-5893
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorCwynar, Elzbietaen
dc.contributor.authorSwiątkowska, Beataen
dc.contributor.authorTomczyk, Jarosławen
dc.date.accessioned2017-08-22T11:37:36Z-
dc.date.available2017-08-22T11:37:36Z-
dc.date.issued2017-03-24-
dc.identifier.citationMedycyna Pracy 2017 Mar 24;68(2):247-258.en
dc.identifier.issn0465-5893-
dc.identifier.pmid28345684-
dc.identifier.doi10.13075/mp.5893.00501-
dc.identifier.urihttp://hdl.handle.net/10146/618128-
dc.description.abstractThe adverse health effects of occupational exposure to asbestos dust may occur several years after first exposure. The objective of the study was to assess the relationship between lesions in the respiratory system and the factors contributing to occupational exposure to asbestos described in the first medical examination as well as to analyze the factors responsible for the progression of these changes in further medical tests.en
dc.description.abstractThe study group comprised 591 former workers of asbestos processing plant "Gambit" in Lubawka. The results of medical examinations carried out in 2001-2012 were assessed. Statistical inference was performed based on bilateral significance tests at the 0.05 level of significance.en
dc.description.abstractA higher risk of interstitial lung changes along with an increase in the cumulative concentration of asbestos was indicated; for the employees with the highest exposure, the adjusted odds ratio (OR) was 1.63 (95% confidence interval (CI): 0.99-2.71), while for changes with the severity degree qualifying for asbestosis diagnosis, the risk was significantly increased, over fivefold higher, compared to subjects employed in the lowest exposure. The analysis of the relationship between the progression of interstitial changes and the exposure to asbestos dust showed a fourfold higher risk of the progression in workers employed in the highest exposure. Mean values of FEV1 (forced expiratory volume in 1 s), FVC (forced vital capacity), FEV1/FVC (forced expiratory volume in 1 s to forced vital capacity) were significantly lower in the subjects working in a higher asbestos exposure. The effect of tobacco smoking on the occurrence of interstitial lung changes and their progression was also confirmed.en
dc.description.abstractThe results of prophylactic medical examinations of the health status of workers formerly employed in the plants using chrysotile indicate the importance andthe need for a long-term clinical follow-up and the promotion of anti-smoking prevention in this group of former employees. Med Pr 2017;68(2):247-258.en
dc.languagepol-
dc.language.isoplen
dc.relation.urlhttp://medpr.imp.lodz.pl/Analiza-zmian-w-obrazie-radiologicznym-pluc-i-zaburzen-czynnosci-wentylacyjnej-pluc-u-pracownikow-zawodowo-narazonych-na-azbest-chryzotylowy-w-przeszlosci,64468,0,2.htmlen
dc.rightsArchived with thanks to Medycyna pracyen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectasbestosisen
dc.subjectchrysotileen
dc.subjectcumulative exposureen
dc.subjectinterstitial lung changesen
dc.subjectoccupational exposureen
dc.subjectspirometric parametersen
dc.titleAnaliza zmian w obrazie radiologicznym pluc i zaburzen czynnosci wentylacyjnej pluc u pracownikow zawodowo narazonych na azbest chryzotylowy w przeszlosci.pl
dc.title.alternativeAnalysis of changes in radiographic lung image and lung ventilation disorders in workers occupationally exposed to chrysotile in the past.en
dc.typeArticleen
dc.contributor.departmentNofer Institute of Occupational Medicine, Lodz, Polanden
dc.identifier.journalMedycyna Pracyen

Related articles on PubMed

This item is licensed under a Creative Commons License
Creative Commons
All Items in ECNIS-NIOM are protected by copyright, with all rights reserved, unless otherwise indicated.