[Application of recombinant latex allergens in diagnostics of occupational latex allergy].

2.50
Hdl Handle:
http://hdl.handle.net/10146/556639
Title:
[Application of recombinant latex allergens in diagnostics of occupational latex allergy].
Authors:
Nowakowska-Swirta, Ewa; Wiszniewska, Marta; Walusiak-Skorupa, Jolanta ( 0000-0003-0836-6800 )
Abstract:
Over many years, allergy to natural rubber latex has been a major problem among health care workers (HCW). The diagnosis of occupational allergy requires methods of high diagnostic accuracy in view of certification implications (e.g., a sick worker quits a job). With the development of molecular methods, the frequency of application of recombinant allergens it the diagnostics of allergic diseases continues to increase. This paper reviews the applicability of laboratory tests which use recombinant allergens in the diagnostics of occupational allergy. The diagnosis of latex allergy is based on the presence of clinical symptoms linked with exposure to latex allergens, positive skin prick tests and detection of specific IgE antibodies to latex in serun. Moreover, in some cases specific challenge tests are conducted. The analysis of literature indicates that applying the panel of recombinant latex allergens in diagnostic tests, cross-reactivity can very likely be excluded and/or sensitization can be confirmed without the need for specific challenge tests, which in case of latex allergens carries a potential risk of aeneralized reactions.
Affiliation:
Nofer Institute of Occupational Medicine, Lodz, Poland
Citation:
Med Pr 2015, 66 (1):85-97
Journal:
Medycyna Pracy
Issue Date:
2015
URI:
http://hdl.handle.net/10146/556639
PubMed ID:
26016048
Additional Links:
http://medpr.imp.lodz.pl/Zastosowanie-alergenow-rekombinowanych-w-diagnostyce-zawodowej-alergii-na-lateks,1952,0,2.html
Type:
Article
Language:
pl
ISSN:
0465-5893
Sponsors:
IMP 11.3 pt. „Zastosowanie alergenowo swoistych przeciwciał IgE dla alergenów rekombinowanych w diagnostyce alergii zawodowej na lateks”.
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorNowakowska-Swirta, Ewaen
dc.contributor.authorWiszniewska, Martaen
dc.contributor.authorWalusiak-Skorupa, Jolantaen
dc.date.accessioned2015-06-10T09:33:58Zen
dc.date.available2015-06-10T09:33:58Zen
dc.date.issued2015en
dc.identifier.citationMed Pr 2015, 66 (1):85-97en
dc.identifier.issn0465-5893en
dc.identifier.pmid26016048en
dc.identifier.urihttp://hdl.handle.net/10146/556639en
dc.description.abstractOver many years, allergy to natural rubber latex has been a major problem among health care workers (HCW). The diagnosis of occupational allergy requires methods of high diagnostic accuracy in view of certification implications (e.g., a sick worker quits a job). With the development of molecular methods, the frequency of application of recombinant allergens it the diagnostics of allergic diseases continues to increase. This paper reviews the applicability of laboratory tests which use recombinant allergens in the diagnostics of occupational allergy. The diagnosis of latex allergy is based on the presence of clinical symptoms linked with exposure to latex allergens, positive skin prick tests and detection of specific IgE antibodies to latex in serun. Moreover, in some cases specific challenge tests are conducted. The analysis of literature indicates that applying the panel of recombinant latex allergens in diagnostic tests, cross-reactivity can very likely be excluded and/or sensitization can be confirmed without the need for specific challenge tests, which in case of latex allergens carries a potential risk of aeneralized reactions.en
dc.description.sponsorshipIMP 11.3 pt. „Zastosowanie alergenowo swoistych przeciwciał IgE dla alergenów rekombinowanych w diagnostyce alergii zawodowej na lateks”.en
dc.languagepolen
dc.language.isoplen
dc.relation.urlhttp://medpr.imp.lodz.pl/Zastosowanie-alergenow-rekombinowanych-w-diagnostyce-zawodowej-alergii-na-lateks,1952,0,2.htmlen
dc.rightsArchived with thanks to Medycyna pracyen
dc.subjectnatural rubber latexen
dc.subjectrecombinant latex allergensen
dc.subjectallergy to latexen
dc.subjectdiagnostic methodsen
dc.subjectoccupational allergyen
dc.subjectcross reactivityen
dc.title[Application of recombinant latex allergens in diagnostics of occupational latex allergy].pl
dc.typeArticleen
dc.contributor.departmentNofer Institute of Occupational Medicine, Lodz, Polanden
dc.identifier.journalMedycyna Pracyen

Related articles on PubMed

This item is licensed under a Creative Commons License
Creative Commons
All Items in ECNIS-NIOM are protected by copyright, with all rights reserved, unless otherwise indicated.