Antiproliferative activity of extracts of some Bolivian medicinal plants.

2.50
Hdl Handle:
http://hdl.handle.net/10146/233171
Title:
Antiproliferative activity of extracts of some Bolivian medicinal plants.
Authors:
Rodrigo, Gloria C.; Almanza, Giovanna R.; Akesson, Bjorn; Duan, Rui-Dong
Abstract:
Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity of the extracts was correlated with the phytochemical characterization. Further studies of the mechanism of action of the bioactive extracts are needed.
Citation:
J. Med. Plant. Res. 2010, 4:2204-2210
Journal:
Journal of Medicinal Plants Research
Issue Date:
4-Nov-2010
URI:
http://hdl.handle.net/10146/233171
Additional Links:
http://www.academicjournals.org/JMPR/abstracts/abstracts/abstracts2010/4Nov/Rodrigo%20et%20al.htm
Type:
Article
Language:
en
ISSN:
1996-0875
Sponsors:
This research was supported by Swedish International Development Agency (Sida) by funding a joint project on Plant Biodiversity between Major University of San Andres, La Paz, Bolivia and Lund University, Sweden. Some support was obtained from the EU NoE ECNIS (513943).
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorRodrigo, Gloria C.en_GB
dc.contributor.authorAlmanza, Giovanna R.en_GB
dc.contributor.authorAkesson, Bjornen_GB
dc.contributor.authorDuan, Rui-Dongen_GB
dc.date.accessioned2012-07-11T11:58:41Z-
dc.date.available2012-07-11T11:58:41Z-
dc.date.issued2010-11-04-
dc.identifier.citationJ. Med. Plant. Res. 2010, 4:2204-2210en_GB
dc.identifier.issn1996-0875-
dc.identifier.urihttp://hdl.handle.net/10146/233171-
dc.description.abstractTwenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity of the extracts was correlated with the phytochemical characterization. Further studies of the mechanism of action of the bioactive extracts are needed.en_GB
dc.description.sponsorshipThis research was supported by Swedish International Development Agency (Sida) by funding a joint project on Plant Biodiversity between Major University of San Andres, La Paz, Bolivia and Lund University, Sweden. Some support was obtained from the EU NoE ECNIS (513943).en_GB
dc.language.isoenen
dc.relation.urlhttp://www.academicjournals.org/JMPR/abstracts/abstracts/abstracts2010/4Nov/Rodrigo%20et%20al.htmen_GB
dc.subjectBolivian plantsen_GB
dc.subjectCell proliferationen_GB
dc.subjectColon canceren_GB
dc.subjectBioactivityen_GB
dc.titleAntiproliferative activity of extracts of some Bolivian medicinal plants.en
dc.typeArticleen
dc.identifier.journalJournal of Medicinal Plants Researchen_GB
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